Project Overview

To design polyethylene glycol diacrylate (PEGdA) hydrogels for the encapsulation of Murine Leydig Tumor Cells (MLTC-1) in an effort to increase cell viability and testosterone secretion. The PEG-dA hydrogels must provide immunoprotection and allow for the effective diffusion of oxygen, nutrients, hormones, and metabolic wastes. The overall goal is to restore the testosterone level of castrated mice via injection or implantation of the PEG-dA encapsulated cells.

Files

• Project Design Specification (October 26, 2006)
• Mid-semester Presentation (October 27, 2006)
• Final-Poster Presentation (December 8, 2006)

Contact Information

Team Members

• Albert Kwansa - Team Leader
• John Harrison - Communicator
• Jacqueline Wong - BSAC
• Eric Lee - BWIG

Advisor and Client

• Prof. William Murphy - Advisor
• Dr. Craig Atwood - Client

Related Projects

• Spring 2007: Microencapsulation of tissues and cells for treatment of hormone-related diseases.
• Fall 2006: Microencapsulation of tissues and cells for treatment of hormone-related diseases
• Spring 2006: Microencapsulation of Leydig Cells
• Fall 2005: Microencapsulation of tissues and cells for treatment of hormone-related diseases