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Microfluidic cell sorter

Creating a microfluidic chip device capable of centering and adjusting flow speed for use in cell sorting

Project Overview

The Skala lab has developed label-free optical signals to sort T-cells by activation state. The next step in their research requires a microfluidic chip to flow the cells at speeds that allow 100's of ms integration time on the detector. The device can be commercial or newly designed, and requires a number of specifications in order to integrate with their system. The function of the device should create single-file cell flow through the interrogation window with a stable core diameter of 20 um to 50 um while ensuring that stability is first maintained in the z direction. Cells should flow through the microfluidic device along with a PBS sheath fluid at a flow speed of 1 mm/s and up to 10x faster.

Team Picture

Team Members (from Left) - Hunter Hefti, Josh Zembles, Sara Wagers, and Caleb Heertz
Team Members (from Left) - Hunter Hefti, Josh Zembles, Sara Wagers, and Caleb Heertz

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Contact Information

Team Members

  • Josh Zembles - Team Leader
  • Sara Wagers - Communicator
  • Hunter Hefti - BSAC & BWIG
  • Caleb Heerts - BPAG

Advisor and Client

  • Prof. Justin Williams - Advisor
  • Dr. Melissa Skala - Client
  • Mr. Emmanuel Contreras - Alternate Contact

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